Treatment of External Genital Warts
Treatment of genital warts is often frustrating for clinicians and patients alike. Unlike single-dose therapy for many bacterial sexually transmitted diseases (STD), genital warts may require multiple applications of a local destructive therapy. Such therapy is often painful and sometimes unsuccessful. Moreover, genital warts commonly recur after “successful” therapy.
Podophyllin has been the most common method of therapy for genital warts in public STD clinics because of its convenience and low cost, but low clearance rates have prompted greater interest in alternative forms of therapy. Previous clinical trials demonstrated clearance rates for podophyllin ranging from 22-77% and have shown that cryotherapy is superior to podophyllin.
Electrosurgery and cryotherapy have been shown to produce clearance rates for genital warts ranging from 63-91%. However, none of these methods are highly successful. Misdiagnosis of other epithelial conditions (pearly penile papules, molluscum contagiosum, fibroepithelial polyps, heterotopic sebaceous glands) as genital warts is a potential source of misclassification.
Response to genital wart therapy is influenced by individual wart area, total wart area, duration, and anatomic site. Newer warts may be more amenable to treatment than older warts because they are less heavily keratinised. Keratinisation would be expected to impede local therapy with podophyllin, but not with more destructive methods such as cryotherapy or electrodesiccation.
In women, anal warts are no more resistant to treatment than genital warts. In contrast, anal warts in gay men may be a marker for immunosuppression, and a recent study found that HIV-induced immunosuppression was clearly related to lower clearance rates for anogenital warts. The higher clearance rate in females may relate to higher rates of spontaneous regression or greater ease of eradication of warts in nonkeratinised areas, compared to keratinised sites.
Public STD program managers and clinic staff, as well as private physicians, should evaluate the feasibility of offering cryotherapy or electrodesiccation to treat genital warts. A comparison of costs and benefits of cryotherapy or electrocautery might show them to be less expensive than podophyllin, since fewer clinic visits are required.
Other than a liquid nitrogen storage tank which must be refilled periodically, the equipment required for cryotherapy is fairly simple: an insulated dispensing container and cotton-tipped wooden sticks. Electrodesiccation is more complicated and time-consuming, since it requires a special apparatus, injection of local anaesthesia, and careful positioning of the patient on a ground pad.
Initial outlay for electrodesiccation equipment is greater than for cryotherapy; however, recurring costs are minimal. Cryotherapy and electrocautery both are considered surgical procedures, and should be performed only by personnel who are adequately trained and supervised. In some jurisdictions, malpractice policies may not allow such procedures to be performed by nurses.
Many clinicians and patients welcome alternative therapies to podophyllin for genital warts. Recently, interferon was licensed for intralesional therapy of external genital warts. However, success with interferon has been limited, and its expense will preclude widespread use. HPVCurative is a new, highly effective and potent way to cure genital warts.
It is valued for its role in the realm of genital warts cures, and has provided total clearance of the infection time after time. It contains certified organic medicinal plant extracts and antiviral essential oils, which have demonstrated the ability to act as an HPV cure in laboratory tests. Users of HPVCurative experience rapid elimination of genital warts without scarring or recurrence.
The treatment is painless and provides superb results when compare to other HPV cures. It eliminates genital warts and restores skin tissue to the state it was in prior to the infection. Since the treatment can effectively remove genital warts and wart-like substances on the genitals, acid or surgical HPV cures may soon become a thing of the past.
HPVCurative is undiluted and unadulterated. It contains stringently certified organic antiviral plant extracts, which have the ability to destroy HPV. The extracts are harvested and distilled by hand for medicinal use. This is essential when creating HPV cures, and it is of critical importance when applying anything to the genitals. To learn more, please go to http://www.bcured.net.
About the Author
staff of Nature Power Company, which is a network company dedicated to promoting customers’ websites and developing softwares. You can go to the following websites to learn more about our natural organic products. http://www.bcured.net http://www.naturespharma.org
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